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HIF-Dependent NFATC1 Activation Upregulates ITGA5 and PLAUR in Intestinal Epithelium in Inflammatory Bowel Disease

Intestinal epithelial cells exist in physiological hypoxia, leading to hypoxia-inducible factor (HIF) activation and supporting barrier function and cell metabolism of the intestinal epithelium. In contrast, pathological hypoxia is a common feature of some chronic disorders, including inflammatory b...

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Detalles Bibliográficos
Autores principales:	Knyazev, Evgeny, Maltseva, Diana, Raygorodskaya, Maria, Shkurnikov, Maxim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632048/ https://www.ncbi.nlm.nih.gov/pubmed/34858489 http://dx.doi.org/10.3389/fgene.2021.791640

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