KCNQ and KCNE Isoform-Dependent Pharmacology Rationalizes Native American Dual Use of Specific Plants as Both Analgesics and Gastrointestinal Therapeutics

Indigenous peoples of the Americas are proficient in botanical medicine. KCNQ family voltage-gated potassium (Kv) channels are sensitive to a variety of ligands, including plant metabolites. Here, we screened methanolic extracts prepared from 40 Californian coastal redwood forest plants for effects...

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Detalles Bibliográficos
Autores principales: Abbott, Geoffrey W., Redford, Kaitlyn E., Yoshimura, Ryan F., Manville, Rían W., Moreira, Luiz, Tran, Kevin, Arena, Grey, Kookootsedes, Alexandra, Lasky, Emma, Gunnison, Elliot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632246/
https://www.ncbi.nlm.nih.gov/pubmed/34858215
http://dx.doi.org/10.3389/fphys.2021.777057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632246/
https://www.ncbi.nlm.nih.gov/pubmed/34858215
http://dx.doi.org/10.3389/fphys.2021.777057

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