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Platelet-Mediated NET Release Amplifies Coagulopathy and Drives Lung Pathology During Severe Influenza Infection

The influenza A virus (IAV) causes a respiratory tract infection with approximately 10% of the population infected by the virus each year. Severe IAV infection is characterized by excessive inflammation and tissue pathology in the lungs. Platelet and neutrophil recruitment to the lung are involved i...

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Detalles Bibliográficos
Autores principales: Kim, Seok-Joo, Carestia, Agostina, McDonald, Braedon, Zucoloto, Amanda Z., Grosjean, Heidi, Davis, Rachelle P., Turk, Madison, Naumenko, Victor, Antoniak, Silvio, Mackman, Nigel, Abdul-Cader, Mohamed Sarjoon, Abdul-Careem, Mohamed Faizal, Hollenberg, Morley D., Jenne, Craig N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632260/
https://www.ncbi.nlm.nih.gov/pubmed/34858432
http://dx.doi.org/10.3389/fimmu.2021.772859