Cargando…

The BAX-binding protein MOAP1 associates with LC3 and promotes closure of the phagophore

MOAP1 (modulator of apoptosis 1) is a BAX-binding protein tightly regulated by the ubiquitin-proteasome system. Apoptotic stimuli stabilize MOAP1 protein and facilitate its interaction with BAX to promote apoptosis. Here we show that in contrast to being resistant to apoptotic stimuli, MOAP1-deficie...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang, Hao-Chun, Tao, Ran N., Tan, Chong Teik, Wu, Ya Jun, Bay, Boon Huat, Yu, Victor C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632279/
https://www.ncbi.nlm.nih.gov/pubmed/33783314
http://dx.doi.org/10.1080/15548627.2021.1896157