WIPI1 promotes fission of endosomal transport carriers and formation of autophagosomes through distinct mechanisms

Autophagosome formation requires PROPPIN/WIPI proteins and monophosphorylated phosphoinositides, such as phosphatidylinositol-3-phosphate (PtdIns3P) or PtdIns5P. This process occurs in association with mammalian endosomes, where the PROPPIN WIPI1 has additional, undefined roles in vesicular traffic....

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Detalles Bibliográficos
Autores principales: De Leo, Maria Giovanna, Berger, Philipp, Mayer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632285/
https://www.ncbi.nlm.nih.gov/pubmed/33685363
http://dx.doi.org/10.1080/15548627.2021.1886830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632285/
https://www.ncbi.nlm.nih.gov/pubmed/33685363
http://dx.doi.org/10.1080/15548627.2021.1886830

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