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WIPI1 promotes fission of endosomal transport carriers and formation of autophagosomes through distinct mechanisms
Autophagosome formation requires PROPPIN/WIPI proteins and monophosphorylated phosphoinositides, such as phosphatidylinositol-3-phosphate (PtdIns3P) or PtdIns5P. This process occurs in association with mammalian endosomes, where the PROPPIN WIPI1 has additional, undefined roles in vesicular traffic....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632285/ https://www.ncbi.nlm.nih.gov/pubmed/33685363 http://dx.doi.org/10.1080/15548627.2021.1886830 |