Cancer-specific type-I interferon receptor signaling promotes cancer stemness and effector CD8+ T-cell exhaustion

Type-I interferon (IFN-I) signaling is critical to maintaining antigen-presenting cell function for anti-tumor immunity. However, recent studies have suggested that IFN-I signaling may also contribute to more aggressive phenotypes, raising the possibility that IFN-I downstream signaling in cancer an...

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Detalles Bibliográficos
Autores principales: Gong, Wang, Donnelly, Christopher R., Heath, Blake R., Bellile, Emily, Donnelly, Lorenza A., Taner, Hülya F., Broses, Luke, Brenner, J. Chad, Chinn, Steven B., Ji, Ru-Rong, Wen, Haitao, Nör, Jacques E., Wang, Jie, Wolf, Gregory T., Xie, Yuying, Lei, Yu Leo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632299/
https://www.ncbi.nlm.nih.gov/pubmed/34858725
http://dx.doi.org/10.1080/2162402X.2021.1997385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632299/
https://www.ncbi.nlm.nih.gov/pubmed/34858725
http://dx.doi.org/10.1080/2162402X.2021.1997385

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