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Vesiculin derived from IGF-II drives increased islet cell mass in a mouse model of pre-diabetes

Pancreatic islet-cell function and volume are both key determinants of the maintenance of metabolic health. Insulin resistance and islet-cell dysfunction often occur in the earlier stages of type 2 diabetes (T2D) progression. The ability of the islet cells to respond to insulin resistance by increas...

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Detalles Bibliográficos
Autores principales: Lee, Kate L., Aitken, Jacqueline F., Li, Xun, Montgomery, Kirsten, Hsu, Huai-L., Williams, Geoffrey M., Brimble, Margaret A., Cooper, Garth J.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632304/
https://www.ncbi.nlm.nih.gov/pubmed/34632959
http://dx.doi.org/10.1080/19382014.2021.1982326