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Epigenetic condensates regulate chromatin activity and tumorigenesis

Alterations of epigenetic modulators are extensively associated with cancer, but their key molecular activities in cancer regulation are often unclear. We discovered that lysine demethylase 6A (KDM6A, also known as UTX) suppresses cancer by forming liquid-like condensates with lysine methyltransfera...

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Detalles Bibliográficos
Autores principales: Shi, Bi, Li, Wei, Jiang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632315/
https://www.ncbi.nlm.nih.gov/pubmed/34859151
http://dx.doi.org/10.1080/23723556.2021.1997040