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Epigenetic condensates regulate chromatin activity and tumorigenesis
Alterations of epigenetic modulators are extensively associated with cancer, but their key molecular activities in cancer regulation are often unclear. We discovered that lysine demethylase 6A (KDM6A, also known as UTX) suppresses cancer by forming liquid-like condensates with lysine methyltransfera...
Autores principales: | Shi, Bi, Li, Wei, Jiang, Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632315/ https://www.ncbi.nlm.nih.gov/pubmed/34859151 http://dx.doi.org/10.1080/23723556.2021.1997040 |
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