ATG7 is dispensable for LC3–PE conjugation in thioglycolate-elicited mouse peritoneal macrophages

Thioglycolate-elicited macrophages exhibit abundant conjugation of LC3 with PE (LC3-II). Among other autophagy-related (ATG) proteins, it is proposed that, like in yeast, both ATG5 and ATG7 are essential for LC3 conjugation. Using atg5-deficient ((−/-)) and atg7(−/-)macrophages, we provide evidence...

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Detalles Bibliográficos
Autores principales: Vujić, Nemanja, Bradić, Ivan, Goeritzer, Madeleine, Kuentzel, Katharina B., Rainer, Silvia, Kratky, Dagmar, Radović, Branislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632316/
https://www.ncbi.nlm.nih.gov/pubmed/33459130
http://dx.doi.org/10.1080/15548627.2021.1874132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632316/
https://www.ncbi.nlm.nih.gov/pubmed/33459130
http://dx.doi.org/10.1080/15548627.2021.1874132

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