Cargando…
ATG7 is dispensable for LC3–PE conjugation in thioglycolate-elicited mouse peritoneal macrophages
Thioglycolate-elicited macrophages exhibit abundant conjugation of LC3 with PE (LC3-II). Among other autophagy-related (ATG) proteins, it is proposed that, like in yeast, both ATG5 and ATG7 are essential for LC3 conjugation. Using atg5-deficient ((−/-)) and atg7(−/-)macrophages, we provide evidence...
Autores principales: | Vujić, Nemanja, Bradić, Ivan, Goeritzer, Madeleine, Kuentzel, Katharina B., Rainer, Silvia, Kratky, Dagmar, Radović, Branislav |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632316/ https://www.ncbi.nlm.nih.gov/pubmed/33459130 http://dx.doi.org/10.1080/15548627.2021.1874132 |
Ejemplares similares
-
Metabolic changes and propensity for inflammation, fibrosis, and cancer in livers of mice lacking lysosomal acid lipase
por: Bradić, Ivan, et al.
Publicado: (2023) -
Defective Lysosomal Lipolysis Causes Prenatal Lipid Accumulation and Exacerbates Immediately after Birth
por: Kuentzel, Katharina B., et al.
Publicado: (2021) -
Off-target effects of the lysosomal acid lipase inhibitors Lalistat-1 and Lalistat-2 on neutral lipid hydrolases
por: Bradić, Ivan, et al.
Publicado: (2022) -
Higher phagocytic activity of thioglycollate-elicited peritoneal macrophages is related to metabolic status of the cells
por: Pavlou, Sofia, et al.
Publicado: (2017) -
Monoglyceride Lipase Deficiency Is Associated with Altered Thrombogenesis in Mice
por: Goeritzer, Madeleine, et al.
Publicado: (2023)