Cargando…

Agonistic nanobodies and antibodies to human VISTA

The V-domain Ig Suppressor of T-cell Activation (VISTA) is an immune checkpoint regulator that suppresses immune responses and is readily expressed on human and murine myeloid cells and T cells. This immunosuppressive pathway can be activated using VISTA agonists. Here, we report the development of...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Yu-Heng Vivian, Sparkes, Amanda, Romão, Ema, Saha, Shrayasee, Gariépy, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632329/
https://www.ncbi.nlm.nih.gov/pubmed/34818120
http://dx.doi.org/10.1080/19420862.2021.2003281