Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation

Hereditary spastic paraplegia (HSP) denotes genetically heterogeneous disorders characterized by leg spasticity due to degeneration of corticospinal axons. SPG11 and SPG15 have a similar clinical course and together are the most prevalent autosomal recessive HSP entity. The respective proteins play...

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Detalles Bibliográficos
Autores principales: Khundadze, Mukhran, Ribaudo, Federico, Hussain, Adeela, Stahlberg, Henry, Brocke-Ahmadinejad, Nahal, Franzka, Patricia, Varga, Rita-Eva, Zarkovic, Milena, Pungsrinont, Thanakorn, Kokal, Miriam, Ganley, Ian G., Beetz, Christian, Sylvester, Marc, Hübner, Christian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632344/
https://www.ncbi.nlm.nih.gov/pubmed/33618608
http://dx.doi.org/10.1080/15548627.2021.1891848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632344/
https://www.ncbi.nlm.nih.gov/pubmed/33618608
http://dx.doi.org/10.1080/15548627.2021.1891848

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