Ataxin-10 Inhibits TNF-α-Induced Endothelial Inflammation via Suppressing Interferon Regulatory Factor-1

Endothelial inflammation is a crucial event in the initiation of atherosclerosis. Here, we identify Ataxin-10 protein as a novel negative modulator of endothelial activation by suppressing IRF-1 transcription activity. The protein level of Ataxin-10 is relatively higher in human vascular endothelial...

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Detalles Bibliográficos
Autores principales: Li, Yong, Zhang, Qi, Li, Na, Ding, Liting, Yi, Jinping, Xiao, Yue, Chen, Shibiao, Huang, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632433/
https://www.ncbi.nlm.nih.gov/pubmed/34858081
http://dx.doi.org/10.1155/2021/7042148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632433/
https://www.ncbi.nlm.nih.gov/pubmed/34858081
http://dx.doi.org/10.1155/2021/7042148

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