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Ataxin-10 Inhibits TNF-α-Induced Endothelial Inflammation via Suppressing Interferon Regulatory Factor-1
Endothelial inflammation is a crucial event in the initiation of atherosclerosis. Here, we identify Ataxin-10 protein as a novel negative modulator of endothelial activation by suppressing IRF-1 transcription activity. The protein level of Ataxin-10 is relatively higher in human vascular endothelial...
Autores principales: | Li, Yong, Zhang, Qi, Li, Na, Ding, Liting, Yi, Jinping, Xiao, Yue, Chen, Shibiao, Huang, Xuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632433/ https://www.ncbi.nlm.nih.gov/pubmed/34858081 http://dx.doi.org/10.1155/2021/7042148 |
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