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Biomarkers and Mechanism Analysis for Polygoni Multiflori Radix Preparata-Induced Liver Injury by UHPLC-Q-TOF-MS-Based Metabolomics

BACKGROUND: Polygonum Multiflorum Radix Preparata (PMP), prepared from Polygonum multiflorum Thunb. (PM), is traditionally valued for its liver and kidney-tonifying effects. However, the previous studies showed that PMP was hepatotoxic, which limited its clinical use. Unfortunately, the potential he...

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Detalles Bibliográficos
Autores principales: Wang, Liming, Wang, Zhida, Xing, Yanchao, Liu, Erwei, Gao, Xiumei, Wang, Linlin, Fu, Zhifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632464/
https://www.ncbi.nlm.nih.gov/pubmed/34858511
http://dx.doi.org/10.1155/2021/7677392