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Biomarkers and Mechanism Analysis for Polygoni Multiflori Radix Preparata-Induced Liver Injury by UHPLC-Q-TOF-MS-Based Metabolomics
BACKGROUND: Polygonum Multiflorum Radix Preparata (PMP), prepared from Polygonum multiflorum Thunb. (PM), is traditionally valued for its liver and kidney-tonifying effects. However, the previous studies showed that PMP was hepatotoxic, which limited its clinical use. Unfortunately, the potential he...
Autores principales: | Wang, Liming, Wang, Zhida, Xing, Yanchao, Liu, Erwei, Gao, Xiumei, Wang, Linlin, Fu, Zhifei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632464/ https://www.ncbi.nlm.nih.gov/pubmed/34858511 http://dx.doi.org/10.1155/2021/7677392 |
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