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lncRNA TUG1 Facilitates Colorectal Cancer Stem Cell Characteristics and Chemoresistance by Enhancing GATA6 Protein Stability

BACKGROUND: Chemoresistance and tumor recurrence lead to high deaths in colorectal cancer (CRC) patients. Cancer stem cells (CSCs) contribute to these pathologic properties, but the exact mechanisms are still poorly understood. This study identified that long noncoding RNA (lncRNA) TUG1 was highly e...

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Detalles Bibliográficos
Autores principales: Sun, Junfeng, Zhou, Hangyuan, Bao, Xingqi, Wu, Yue, Jia, Haowei, Zhao, Hongchao, Liu, Guanghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632465/
https://www.ncbi.nlm.nih.gov/pubmed/34858502
http://dx.doi.org/10.1155/2021/1075481