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Hypermethylation of the Promoter of miR-338-5p Mediates Aberrant Expression of ETS-1 and Is Correlated With Disease Severity Of Astrocytoma Patients

The pro-oncogene ETS-1 (E26 transformation-specific sequence 1) is a key regulator of the proliferation and invasion of cancer cells. The present work examined the correlation of the aberrant expression of ETS-1 with histological or clinical classification of astrocytoma: grade I (pilocytic astrocyt...

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Detalles Bibliográficos
Autores principales: Wang, Junping, Huo, Cheng, Yin, Jinzhu, Tian, Lixia, Ma, Lili, Wang, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632532/
https://www.ncbi.nlm.nih.gov/pubmed/34858853
http://dx.doi.org/10.3389/fonc.2021.773644