Intranasal Delivery of MVA Vector Vaccine Induces Effective Pulmonary Immunity Against SARS-CoV-2 in Rodents

Antigen-specific tissue-resident memory T cells (Trms) and neutralizing IgA antibodies provide the most effective protection of the lungs from viral infections. To induce those essential components of lung immunity against SARS-CoV-2, we tested various immunization protocols involving intranasal del...

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Detalles Bibliográficos
Autores principales: Bošnjak, Berislav, Odak, Ivan, Barros-Martins, Joana, Sandrock, Inga, Hammerschmidt, Swantje I., Permanyer, Marc, Patzer, Gwendolyn E., Greorgiev, Hristo, Gutierrez Jauregui, Rodrigo, Tscherne, Alina, Schwarz, Jan Hendrik, Kalodimou, Georgia, Ssebyatika, George, Ciurkiewicz, Malgorzata, Willenzon, Stefanie, Bubke, Anja, Ristenpart, Jasmin, Ritter, Christiane, Tuchel, Tamara, Meyer zu Natrup, Christian, Shin, Dai-Lun, Clever, Sabrina, Limpinsel, Leonard, Baumgärtner, Wolfgang, Krey, Thomas, Volz, Asisa, Sutter, Gerd, Förster, Reinhold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632543/
https://www.ncbi.nlm.nih.gov/pubmed/34858430
http://dx.doi.org/10.3389/fimmu.2021.772240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632543/
https://www.ncbi.nlm.nih.gov/pubmed/34858430
http://dx.doi.org/10.3389/fimmu.2021.772240

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