Anti-TLR7 Antibody Protects Against Lupus Nephritis in NZBWF1 Mice by Targeting B Cells and Patrolling Monocytes

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by autoantibody production and multiple organ damage. Toll-like receptor 7 (TLR7), an innate immune RNA sensor expressed in monocytes/macrophages, dendritic cells (DCs), and B cells, promotes disease progression. However, litt...

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Detalles Bibliográficos
Autores principales: Murakami, Yusuke, Fukui, Ryutaro, Tanaka, Reika, Motoi, Yuji, Kanno, Atsuo, Sato, Ryota, Yamaguchi, Kiyoshi, Amano, Hirofumi, Furukawa, Yoichi, Suzuki, Hitoshi, Suzuki, Yusuke, Tamura, Naoto, Yamashita, Naomi, Miyake, Kensuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632649/
https://www.ncbi.nlm.nih.gov/pubmed/34868046
http://dx.doi.org/10.3389/fimmu.2021.777197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632649/
https://www.ncbi.nlm.nih.gov/pubmed/34868046
http://dx.doi.org/10.3389/fimmu.2021.777197

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