Co-Administration of Vonoprazan, Not Tegoprazan, Affects the Pharmacokinetics of Atorvastatin in Healthy Male Subjects

Potassium-competitive acid blocker is a new class of drugs inhibiting gastric acid. It is controversial that vonoprazan showed the inhibitory activities of cytochrome P450 3A4. This study aimed to evaluate the pharmacokinetics (PK) of atorvastatin and safety when atorvastatin was administered alone...

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Detalles Bibliográficos
Autores principales: Hwang, Sejung, Ko, Jae-Wook, Lee, Heechan, Kim, Seokuee, Kim, Bongtae, Song, Geun Seog, Kim, Jungryul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632694/
https://www.ncbi.nlm.nih.gov/pubmed/34867368
http://dx.doi.org/10.3389/fphar.2021.754849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632694/
https://www.ncbi.nlm.nih.gov/pubmed/34867368
http://dx.doi.org/10.3389/fphar.2021.754849

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