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Differential Effects of Oleic and Palmitic Acids on Lipid Droplet-Mitochondria Interaction in the Hepatic Cell Line HepG2

Fatty acid overload, either of the saturated palmitic acid (PA) or the unsaturated oleic acid (OA), causes triglyceride accumulation into specialized organelles termed lipid droplets (LD). However, only PA overload leads to liver damage mediated by mitochondrial dysfunction. Whether these divergent...

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Detalles Bibliográficos
Autores principales: Eynaudi, Andrea, Díaz-Castro, Francisco, Bórquez, Juan Carlos, Bravo-Sagua, Roberto, Parra, Valentina, Troncoso, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632770/
https://www.ncbi.nlm.nih.gov/pubmed/34869541
http://dx.doi.org/10.3389/fnut.2021.775382