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Prokaryotic reverse transcriptases: from retroelements to specialized defense systems

Reverse transcriptases (RTs) catalyze the polymerization of DNA from an RNA template. These enzymes were first discovered in RNA tumor viruses in 1970, but it was not until 1989 that they were found in prokaryotes as a key component of retrons. Apart from RTs encoded by the ‘selfish’ mobile retroele...

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Detalles Bibliográficos
Autores principales: González-Delgado, Alejandro, Mestre, Mario Rodríguez, Martínez-Abarca, Francisco, Toro, Nicolás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632793/
https://www.ncbi.nlm.nih.gov/pubmed/33983378
http://dx.doi.org/10.1093/femsre/fuab025