Disparate effects of MMP and TIMP modulation on coronary atherosclerosis and associated myocardial fibrosis

Matrix metalloproteinase (MMP) activity is tightly regulated by the endogenous tissue inhibitors (TIMPs), and dysregulated activity contributes to extracellular matrix remodelling. Accordingly, MMP/TIMP balance is associated with atherosclerotic plaque progression and instability, alongside adverse...

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Detalles Bibliográficos
Autores principales: Kremastiotis, Georgios, Handa, Ishita, Jackson, Christopher, George, Sarah, Johnson, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632906/
https://www.ncbi.nlm.nih.gov/pubmed/34848763
http://dx.doi.org/10.1038/s41598-021-02508-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632906/
https://www.ncbi.nlm.nih.gov/pubmed/34848763
http://dx.doi.org/10.1038/s41598-021-02508-4

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