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Immunoprotective effect of an in silico designed multiepitope cancer vaccine with BORIS cancer-testis antigen target in a murine mammary carcinoma model

In our previous study, immunoinformatic tools were used to design a novel multiepitope cancer vaccine based on the most immunodominant regions of BORIS cancer-testis antigen. The final vaccine construct was an immunogenic, non-allergenic, and stable protein consisted of multiple cytotoxic T lymphocy...

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Detalles Bibliográficos
Autores principales: Mahdevar, Elham, Kefayat, Amirhosein, Safavi, Ashkan, Behnia, Amirhossein, Hejazi, Seyed Hossein, Javid, Amaneh, Ghahremani, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632969/
https://www.ncbi.nlm.nih.gov/pubmed/34848739
http://dx.doi.org/10.1038/s41598-021-01770-w