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Immunoprotective effect of an in silico designed multiepitope cancer vaccine with BORIS cancer-testis antigen target in a murine mammary carcinoma model
In our previous study, immunoinformatic tools were used to design a novel multiepitope cancer vaccine based on the most immunodominant regions of BORIS cancer-testis antigen. The final vaccine construct was an immunogenic, non-allergenic, and stable protein consisted of multiple cytotoxic T lymphocy...
Autores principales: | Mahdevar, Elham, Kefayat, Amirhosein, Safavi, Ashkan, Behnia, Amirhossein, Hejazi, Seyed Hossein, Javid, Amaneh, Ghahremani, Fatemeh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632969/ https://www.ncbi.nlm.nih.gov/pubmed/34848739 http://dx.doi.org/10.1038/s41598-021-01770-w |
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