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Natural killer cell-derived exosomal miR-1249-3p attenuates insulin resistance and inflammation in mouse models of type 2 diabetes

Natural killer (NK) cells have been suggested to be associated with type 2 diabetes by regulating systemic inflammation. However, the mechanism by which NK cells regulate insulin sensitivity remains unknown. This study shows that NK-derived exosomes from lean mice attenuate obesity-induced insulin r...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Li, Mengwei, Chen, Lin, Bian, Huan, Chen, Xiangying, Zheng, Huilin, Yang, Peiwei, Chen, Quan, Xu, Hanmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632983/
https://www.ncbi.nlm.nih.gov/pubmed/34848693
http://dx.doi.org/10.1038/s41392-021-00805-y