Inhibition of SYK and cSrc kinases can protect bone and cartilage in preclinical models of osteoarthritis and rheumatoid arthritis

The pathophysiology of osteoarthritis (OA) includes the destruction of subchondral bone tissue and inflammation of the synovium. Thus, an effective disease-modifying treatment should act on both of these pathogenetic components. It is known that cSrc kinase is involved in bone and cartilage remodeli...

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Detalles Bibliográficos
Autores principales: Novikov, F. N., Panova, M. V., Titov, I. Y., Stroylov, V. S., Stroganov, O. V., Chilov, G. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632988/
https://www.ncbi.nlm.nih.gov/pubmed/34848799
http://dx.doi.org/10.1038/s41598-021-02568-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632988/
https://www.ncbi.nlm.nih.gov/pubmed/34848799
http://dx.doi.org/10.1038/s41598-021-02568-6

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