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Structural basis for anti-CRISPR repression mediated by bacterial operon proteins Aca1 and Aca2

It has been shown that phages have evolved anti-CRISPR (Acr) proteins to inhibit host CRISPR-Cas systems. Most acr genes are located upstream of anti-CRISPR-associated (aca) genes, which is instrumental for identifying these acr genes. Thus far, eight Aca families (Aca1–Aca8) have been identified, a...

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Detalles Bibliográficos
Autores principales: Liu, Yanhong, Zhang, Linsheng, Guo, Maochao, Chen, Liu, Wu, Baixing, Huang, Hongda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633003/
https://www.ncbi.nlm.nih.gov/pubmed/34756887
http://dx.doi.org/10.1016/j.jbc.2021.101357