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Human adipose-derived stromal/stem cells expressing doublecortin improve cartilage repair in rabbits and monkeys

Localized cartilage lesions in early osteoarthritis and acute joint injuries are usually treated surgically to restore function and relieve pain. However, a persistent clinical challenge remains in how to repair the cartilage lesions. We expressed doublecortin (DCX) in human adipose-derived stromal/...

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Detalles Bibliográficos
Autores principales: Ge, Dongxia, O’Brien, Michael J., Savoie, Felix H., Gimble, Jeffrey M., Wu, Xiying, Gilbert, Margaret H., Clark-Patterson, Gabrielle L., Schuster, Jason D., Miller, Kristin S., Wang, Alun, Myers, Leann, You, Zongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633050/
https://www.ncbi.nlm.nih.gov/pubmed/34848747
http://dx.doi.org/10.1038/s41536-021-00192-6