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RNF4 Regulates the BLM Helicase in Recovery From Replication Fork Collapse

Sumoylation is an important enhancer of responses to DNA replication stress and the SUMO-targeted ubiquitin E3 ligase RNF4 regulates these responses by ubiquitylation of sumoylated DNA damage response factors. The specific targets and functional consequences of RNF4 regulation in response to replica...

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Detalles Bibliográficos
Autores principales: Ellis, Nathan, Zhu, Jianmei, Yagle, Mary K, Yang, Wei-Chih, Huang, Jing, Kwako, Alexander, Seidman, Michael M., Matunis, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633118/
https://www.ncbi.nlm.nih.gov/pubmed/34868226
http://dx.doi.org/10.3389/fgene.2021.753535