Highly sensitive detection of driver mutations from cytological samples and cfDNA in lung cancer

BACKGROUND: Bronchoscopy is a minimally invasive procedure for establishing the diagnosis of lung cancer. It sometimes fails to obtain tissue samples but readily collects cytological samples. METHODS: We developed PNA‐LNA dual‐PCR (PLDP), which amplified mutant sequences by a high‐fidelity DNA polym...

Descripción completa

Detalles Bibliográficos
Autores principales: Fujita, Kazutaka, Nakayama, Masayuki, Sata, Masafumi, Nagai, Yoshiaki, Hisata, Shu, Mato, Naoko, Suzuki, Takuji, Bando, Masashi, Hizawa, Nobuyuki, Hagiwara, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633228/
https://www.ncbi.nlm.nih.gov/pubmed/34617674
http://dx.doi.org/10.1002/cam4.4330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633228/
https://www.ncbi.nlm.nih.gov/pubmed/34617674
http://dx.doi.org/10.1002/cam4.4330

Ejemplares similares