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Highly sensitive detection of driver mutations from cytological samples and cfDNA in lung cancer

BACKGROUND: Bronchoscopy is a minimally invasive procedure for establishing the diagnosis of lung cancer. It sometimes fails to obtain tissue samples but readily collects cytological samples. METHODS: We developed PNA‐LNA dual‐PCR (PLDP), which amplified mutant sequences by a high‐fidelity DNA polym...

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Detalles Bibliográficos
Autores principales:	Fujita, Kazutaka, Nakayama, Masayuki, Sata, Masafumi, Nagai, Yoshiaki, Hisata, Shu, Mato, Naoko, Suzuki, Takuji, Bando, Masashi, Hizawa, Nobuyuki, Hagiwara, Koichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633228/ https://www.ncbi.nlm.nih.gov/pubmed/34617674 http://dx.doi.org/10.1002/cam4.4330

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