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Dimensional reduction of phenotypes from 53 000 mouse models reveals a diverse landscape of gene function

 : Animal models have long been used to study gene function and the impact of genetic mutations on phenotype. Through the research efforts of thousands of research groups, systematic curation of published literature and high-throughput phenotyping screens, the collective body of knowledge for the mo...

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Detalles Bibliográficos
Autores principales: Konopka, Tomasz, Vestito, Letizia, Smedley, Damian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633315/
https://www.ncbi.nlm.nih.gov/pubmed/34870209
http://dx.doi.org/10.1093/bioadv/vbab026