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Alleviative Effect of Alpha-Lipoic Acid on Cognitive Impairment in High-Fat Diet and Streptozotocin-Induced Type 2 Diabetic Rats

Background: The intricate relationship between type 2 diabetes mellitus (T2DM) and Alzheimer’s disease (AD) suggests that insulin is involved in modulating AD-related proteins. Alpha-lipoic acid (ALA) can improve insulin resistance (IR) in diabetic rats. However, the role of ALA in alleviating the c...

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Detalles Bibliográficos
Autores principales: Ko, Chih-Yuan, Xu, Jian-Hua, Lo, Yangming Martin, Tu, Rong-Syuan, Wu, James Swi-Bea, Huang, Wen-Chung, Shen, Szu-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633445/
https://www.ncbi.nlm.nih.gov/pubmed/34867302
http://dx.doi.org/10.3389/fnagi.2021.774477