Hepatocellular Carcinoma Cells Are Protected From Immunolysis by Mesenchymal Stromal Cells Through Indoleamine 2,3 Dioxygenase

B7 family proteins serve as checkpoint molecules that protect tumors from T cell mediated lysis. Tryptophan degrading enzymes indoleamine 2,3 dioxygenase (IDO) and tryptophan 2,3 dioxygenase (TDO) also induce T cell immune tolerance. However, little is known about the relative contribution of B7 mol...

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Detalles Bibliográficos
Autores principales: Chinnadurai, Raghavan, Porter, Amanda Paige, Patel, Mihir, Lipat, Ariel Joy, Forsberg, Mathews H., Rajan, Devi, Hematti, Peiman, Capitini, Christian M., Bruker, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633446/
https://www.ncbi.nlm.nih.gov/pubmed/34869307
http://dx.doi.org/10.3389/fcell.2021.715905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633446/
https://www.ncbi.nlm.nih.gov/pubmed/34869307
http://dx.doi.org/10.3389/fcell.2021.715905

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