Combination of antiseizure medications phenobarbital, ketamine, and midazolam reduces soman‐induced epileptogenesis and brain pathology in rats

OBJECTIVE: Cholinergic‐induced status epilepticus (SE) is associated with a loss of synaptic gamma‐aminobutyric acid A receptors (GABA(A)R) and an increase in N‐methyl‐D‐aspartate receptors (NMDAR) and amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptors (AMPAR) that may contribute to pharma...

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Detalles Bibliográficos
Autores principales: Lumley, Lucille A., Marrero‐Rosado, Brenda, Rossetti, Franco, Schultz, Caroline R., Stone, Michael F., Niquet, Jerome, Wasterlain, Claude G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full‐length Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633481/
https://www.ncbi.nlm.nih.gov/pubmed/34657398
http://dx.doi.org/10.1002/epi4.12552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633481/
https://www.ncbi.nlm.nih.gov/pubmed/34657398
http://dx.doi.org/10.1002/epi4.12552

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