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AAMP promotes colorectal cancermetastasis by suppressing SMURF2-mediatedubiquitination and degradation of RhoA

Metastasis is considered the leading cause of cancer death due to the limited possibilities to therapeutically target this process. How the ubiquitination machinery contributes to metastasis remains underexplored. Angio-associated migratory cell protein (AAMP), a ubiquitously expressed protein invol...

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Detalles Bibliográficos
Autores principales: Wu, Yuhui, Liu, Bofang, Lin, Weiqiang, Zhao, Rongjie, Han, Weidong, Xie, Jiansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633529/
https://www.ncbi.nlm.nih.gov/pubmed/34901393
http://dx.doi.org/10.1016/j.omto.2021.11.007