Costunolide-Induced Apoptosis via Promoting the Reactive Oxygen Species and Inhibiting AKT/GSK3β Pathway and Activating Autophagy in Gastric Cancer

Objective: Costunolide (Cos) is a sesquiterpene lactone extracted from chicory. Although it possesses anti-tumor effects, the underlying molecular mechanism against gastric cancer cells remains unclear. This study aimed to explore the effect and potential mechanism of Cos on gastric cancer. Methods:...

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Detalles Bibliográficos
Autores principales: Xu, Cuixiang, Huang, Xiaoyan, Lei, Xiaohua, Jin, Zhankui, Wu, Min, Liu, Xiao, Huang, Yubin, Zhao, Xiangrong, Xiong, Yue, Sun, Jingying, Duan, Xianglong, Wang, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633576/
https://www.ncbi.nlm.nih.gov/pubmed/34869312
http://dx.doi.org/10.3389/fcell.2021.722734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633576/
https://www.ncbi.nlm.nih.gov/pubmed/34869312
http://dx.doi.org/10.3389/fcell.2021.722734

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