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Suppression of Ribosome Biogenesis by Targeting WD Repeat Domain 12 (WDR12) Inhibits Glioma Stem-Like Cell Growth

Glioma stem-like cells (GSCs) are a subset of tumor cells that initiate malignant growth and promote the therapeutic resistance of glioblastoma, the most lethal primary brain tumor. Ribosome biogenesis is an essential cellular process to maintain cell growth, but its regulatory mechanism in GSCs rem...

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Detalles Bibliográficos
Autores principales: Mi, Lanjuan, Qi, Qinghui, Ran, Haowen, Chen, Lishu, Li, Da, Xiao, Dake, Wu, Jiaqi, Cai, Yan, Zhang, Songyang, Li, Yuanyuan, Li, Bohan, Xie, Jiong, Huang, Haohao, Li, Tao, Zhou, Tao, Li, Ailing, Qi, Ji, Li, Fangye, Man, Jianghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633585/
https://www.ncbi.nlm.nih.gov/pubmed/34868955
http://dx.doi.org/10.3389/fonc.2021.751792