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ChiTaH: a fast and accurate tool for identifying known human chimeric sequences from high-throughput sequencing data

Fusion genes or chimeras typically comprise sequences from two different genes. The chimeric RNAs of such joined sequences often serve as cancer drivers. Identifying such driver fusions in a given cancer or complex disease is important for diagnosis and treatment. The advent of next-generation seque...

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Detalles Bibliográficos
Autores principales: Detroja, Rajesh, Gorohovski, Alessandro, Giwa, Olawumi, Baum, Gideon, Frenkel-Morgenstern, Milana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633610/
https://www.ncbi.nlm.nih.gov/pubmed/34859212
http://dx.doi.org/10.1093/nargab/lqab112