Cargando…

ChiTaH: a fast and accurate tool for identifying known human chimeric sequences from high-throughput sequencing data

Fusion genes or chimeras typically comprise sequences from two different genes. The chimeric RNAs of such joined sequences often serve as cancer drivers. Identifying such driver fusions in a given cancer or complex disease is important for diagnosis and treatment. The advent of next-generation seque...

Descripción completa

Detalles Bibliográficos
Autores principales:	Detroja, Rajesh, Gorohovski, Alessandro, Giwa, Olawumi, Baum, Gideon, Frenkel-Morgenstern, Milana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Methods Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633610/ https://www.ncbi.nlm.nih.gov/pubmed/34859212 http://dx.doi.org/10.1093/nargab/lqab112

Ejemplares similares

ChiTaRS 5.0: the comprehensive database of chimeric transcripts matched with druggable fusions and 3D chromatin maps
por: Balamurali, Deepak, et al.
Publicado: (2020)

ChiTaRS 2.1—an improved database of the chimeric transcripts and RNA-seq data with novel sense–antisense chimeric RNA transcripts
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2014)

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2013)

ChiTaRS-3.1—the enhanced chimeric transcripts and RNA-seq database matched with protein–protein interactions
por: Gorohovski, Alessandro, et al.
Publicado: (2017)

ChiPPI: a novel method for mapping chimeric protein–protein interactions uncovers selection principles of protein fusion events in cancer
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2017)

The Landscape of Novel Expressed Chimeric RNAs in Rheumatoid Arthritis
por: Detroja, Rajesh, et al.
Publicado: (2022)

Computational analysis of sense-antisense chimeric transcripts reveals their potential regulatory features and the landscape of expression in human cells
por: Mukherjee, Sumit, et al.
Publicado: (2021)

The Landscape of Expressed Chimeric Transcripts in the Blood of Severe COVID-19 Infected Patients
por: Mukherjee, Sunanda Biswas, et al.
Publicado: (2023)

COVID19 Drug Repository: text-mining the literature in search of putative COVID19 therapeutics
por: Tworowski, Dmitry, et al.
Publicado: (2020)

EvoProDom: evolutionary modeling of protein families by assessing translocations of protein domains
por: Carmi, Gon, et al.
Publicado: (2021)

Novel domain combinations in proteins encoded by chimeric transcripts
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2012)

ProtFus: A Comprehensive Method Characterizing Protein-Protein Interactions of Fusion Proteins
por: Tagore, Somnath, et al.
Publicado: (2019)

The chromatin remodeler Chd1 regulates cohesin in budding yeast and humans
por: Boginya, Alexandra, et al.
Publicado: (2019)

Emerging Role of Chimeric RNAs in Cell Plasticity and Adaptive Evolution of Cancer Cells
por: Mukherjee, Sumit, et al.
Publicado: (2021)

Immunoinformatics and Structural Analysis for Identification of Immunodominant Epitopes in SARS-CoV-2 as Potential Vaccine Targets
por: Mukherjee, Sumit, et al.
Publicado: (2020)

Design principles of gene evolution for niche adaptation through changes in protein–protein interaction networks
por: Carmi, Gon, et al.
Publicado: (2020)

Seasonal UV exposure and vitamin D: association with the dynamics of COVID‐19 transmission in Europe
por: Mukherjee, Sunanda Biswas, et al.
Publicado: (2021)

Clinical and Molecular Characterization of a Rare Case of BNT162b2 mRNA COVID-19 Vaccine-Associated Myositis
por: Magen, Eli, et al.
Publicado: (2022)

Accurate multiplexing and filtering for high-throughput amplicon-sequencing
por: Esling, Philippe, et al.
Publicado: (2015)

NARASIMHA: Novel Assay based on Targeted RNA Sequencing to Identify ChiMeric Gene Fusions in Hematological Malignancies
por: Patkar, Nikhil, et al.
Publicado: (2020)

The genome sequence of the Grey Chi, Antitype chi (Linnaeus, 1761)
por: Lees, David
Publicado: (2023)

Detection of gene mutations and gene–gene fusions in circulating cell‐free DNA of glioblastoma patients: an avenue for clinically relevant diagnostic analysis
por: Palande, Vikrant, et al.
Publicado: (2022)

Accurate Diagnostics for Bovine tuberculosis Based on High-Throughput Sequencing
por: Churbanov, Alexander, et al.
Publicado: (2012)

The Association of Previous Vaccination with Live-Attenuated Varicella Zoster Vaccine and COVID-19 Positivity: An Israeli Population-Based Study
por: Merzon, Eugene, et al.
Publicado: (2022)

Identification of Known and Novel MicroRNAs in Raspberry Organs Through High-Throughput Sequencing
por: Yan, Gengxuan, et al.
Publicado: (2020)

High-throughput sequencing reveals the presence of novel and known viruses in diseased Paris yunnanensis
por: Lan, Ping-xiu, et al.
Publicado: (2022)

Incipient Sympatric Speciation and Evolution of Soil Bacteria Revealed by Metagenomic and Structured Non-Coding RNAs Analysis
por: Mukherjee, Sumit, et al.
Publicado: (2022)

HaploJuice : accurate haplotype assembly from a pool of sequences with known relative concentrations
por: Wong, Thomas K. F., et al.
Publicado: (2018)

Chimeras taking shape: Potential functions of proteins encoded by chimeric RNA transcripts
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2012)

Altered Expression and Localization of Tumor Suppressive E3 Ubiquitin Ligase SMURF2 in Human Prostate and Breast Cancer
por: Emanuelli, Andrea, et al.
Publicado: (2019)

Accurate and exact CNV identification from targeted high-throughput sequence data
por: Nord, Alex S, et al.
Publicado: (2011)

SINA: Accurate high-throughput multiple sequence alignment of ribosomal RNA genes
por: Pruesse, Elmar, et al.
Publicado: (2012)

Medium throughput bisulfite sequencing for accurate detection of 5-methylcytosine and 5-hydroxymethylcytosine
por: Chen, Gary G., et al.
Publicado: (2017)

Identification of Known and Novel microRNAs and Their Targets in Peach (Prunus persica) Fruit by High-Throughput Sequencing
por: Zhang, Chunhua, et al.
Publicado: (2016)

Fast and accurate relatedness estimation from high-throughput sequencing data in the presence of inbreeding
por: Hanghøj, Kristian, et al.
Publicado: (2019)

A standardized framework for accurate, high-throughput genotyping of recombinant and non-recombinant viral sequences
por: Alcantara, Luiz Carlos Junior, et al.
Publicado: (2009)

Accurate Inference of Tumor Purity and Absolute Copy Numbers From High-Throughput Sequencing Data
por: Yuan, Xiguo, et al.
Publicado: (2020)

Validation of next-generation sequencing-based chimerism testing for accurate detection and monitoring of engraftment in hematopoietic stem cell transplantation
por: Kakodkar, Pramath, et al.
Publicado: (2023)

Identification of Known and Novel Arundo donax L. MicroRNAs and Their Targets Using High-Throughput Sequencing and Degradome Analysis
por: Rotunno, Silvia, et al.
Publicado: (2022)

tRNA methylation resolves codon usage bias at the limit of cell viability
por: Masuda, Isao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_j7iiqgahvds5jmjbqekeful30o