Cargando…

Structure-based deep learning for binding site detection in nucleic acid macromolecules

Structure-based drug design (SBDD) targeting nucleic acid macromolecules, particularly RNA, is a gaining momentum research direction that already resulted in several FDA-approved compounds. Similar to proteins, one of the critical components in SBDD for RNA is the correct identification of the bindi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kozlovskii, Igor, Popov, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633674/
https://www.ncbi.nlm.nih.gov/pubmed/34859211
http://dx.doi.org/10.1093/nargab/lqab111