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Therapeutic effects of an innovative BS-HH-002 drug on pancreatic cancer cells via induction of complete MCL-1 degradation

BS-HH-002 is a newly developed drug with excellent antitumor activity, which resulted from the modification and optimization of the side structure of the homoharringtonine (HHT). It is particularly efficient in treatment for acute myeloid leukemia and myelodysplastic syndromes. Here we tested whethe...

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Detalles Bibliográficos
Autores principales: Wang, A-min, Qiu, Ru, Zhang, Duo, Zhao, Xiao-yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633684/
https://www.ncbi.nlm.nih.gov/pubmed/34847421
http://dx.doi.org/10.1016/j.tranon.2021.101288