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Therapeutic effects of an innovative BS-HH-002 drug on pancreatic cancer cells via induction of complete MCL-1 degradation
BS-HH-002 is a newly developed drug with excellent antitumor activity, which resulted from the modification and optimization of the side structure of the homoharringtonine (HHT). It is particularly efficient in treatment for acute myeloid leukemia and myelodysplastic syndromes. Here we tested whethe...
Autores principales: | Wang, A-min, Qiu, Ru, Zhang, Duo, Zhao, Xiao-yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633684/ https://www.ncbi.nlm.nih.gov/pubmed/34847421 http://dx.doi.org/10.1016/j.tranon.2021.101288 |
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