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Substrate recognition determinants of human eIF2α phosphatases

Phosphorylation of the translation initiation factor eIF2α is a rapid and vital cellular defence against many forms of stress. In mammals, the levels of eIF2α phosphorylation are set through the antagonistic action of four protein kinases and two heterodimeric protein phosphatases. The phosphatases...

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Detalles Bibliográficos
Autores principales: Hodgson, George, Andreeva, Antonina, Bertolotti, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633803/
https://www.ncbi.nlm.nih.gov/pubmed/34847777
http://dx.doi.org/10.1098/rsob.210205