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Impact of chromosomal organization on epigenetic drift and domain stability revealed by physics-based simulations
We examine the relationship between the size of domains of epigenetic marks and the stability of those domains using our theoretical model that captures the physical mechanisms governing the maintenance of epigenetic modifications. We focus our study on histone H3 lysine-9 trimethylation, one of the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633838/ https://www.ncbi.nlm.nih.gov/pubmed/34687722 http://dx.doi.org/10.1016/j.bpj.2021.10.019 |