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Peiminine Induces G0/G1-Phase Arrest, Apoptosis, and Autophagy via the ROS/JNK Signaling Pathway in Human Osteosarcoma Cells in Vitro and in Vivo

Aims: Peiminine has been reported to have various pharmacological properties, including anticancer activity. In this study, we investigated the effect of this alkaloid on osteosarcoma and explored the underlying mechanisms. Methods: To evaluate the antiosteosarcoma effects of peiminine in vitro, cel...

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Detalles Bibliográficos
Autores principales: Yu, Lei, Chen, Yuxi, Yuan, Shaohui, Cao, Yang, Bi, Zhenggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633898/
https://www.ncbi.nlm.nih.gov/pubmed/34867399
http://dx.doi.org/10.3389/fphar.2021.770846